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Amino Acid May Help Reduce Cocaine Cravings

23.10.09

The results were presented at Neuroscience 2009, the annual meeting of the Society for Neuroscience and the largest in the world emerging from the new brain science and the constitution.

"Our discovery suggests a promising strategy for restoration of the cocaine, for which there is no approved treatment," said the author Khaled Moussawi around the Medical University of South Carolina in Charleston.

Cocaine is an addictive drug enthusiasm characterized by frequent relapses.The late model progress in brain imaging are helping scientists learn what goes into the understanding when a person is addicted to the drug exposure associated "cues" that need to relax - and advance to the relapse. They found that repeated exposure to psychoactive substances such as cocaine causes an imbalance in the circuits of reward and sagacity exercise regulatory power cognitive.

One of these circuits is a process involving glutamate, a neurotransmitter.In the well-known study, Moussaoui and his colleagues found that NAC restored healthy functioning of this circuit in rats that had already been addicted to cocaine. In combination, after receiving NAC, the previously cocaine-dependent rats did not re-engage in drug-seeking behavior, even in the presence of cues associated with drugs.